長期経過後肝転移をきたした十二指腸・小腸平滑筋肉腫の２例

• 米田 浩二

  大阪医科大学一般・消化器外科

• 平松 昌子

  大阪医科大学一般・消化器外科

• 左古 昌蔵

  大阪医科大学一般・消化器外科

• 谷川 允彦

  大阪医科大学一般・消化器外科

• 芝山 雄老

  大阪医科大学病理

書誌事項

タイトル別名

• Two patients with hepatic metastasis from leiomyosarcoma of the duodenum or small intestine after long disease-free periods.

抄録

We experienced two patients with hepatic metastasis developed about 8 years after resection of leiomyosarcoma of the duodenum or small intestine, in whom hepatectomy was successfully performed. In this study, factors that disturbed the growth of metastatic foci in them were investigated. And we reviewed the literature in terms of the correlations among tumor diameter of the primary lesion which is considered useful for the malignancy assessment, mitotic index (MI), and time from the resection of the primary foci to hepatic metastasis. The metastatic hepatic tumors had two characteristic features, namely formation of fibrous capsule and infiltration of cytotoxic T lymphocytes (CD8⁺T cells). Fibrous capsule might disturb blood circulation to the tumors and induce necrosis of the tumor cells. And cytotoxic T lymphocytes might lead to damage of the tumor cells. Accordingly, the two features might contribute to inhibition of the growth of metastatic hepatic tumors and link with favorable prognosis in the present cases. There was no significant correlation between MI and the time to the hepatic metastasis.

収録刊行物

• 日本臨床外科学会雑誌

  日本臨床外科学会雑誌 62 (3), 684-688, 2001

  日本臨床外科学会

キーワード

• 十二指腸・小腸平滑筋肉腫
• 肝転移
• 腫瘍発育速度

詳細情報

• CRID: 1390282679822860672
• NII論文ID: 130003602425
• NII論文ID: 10008388796
• NII書誌ID: AA11189709
• DOI: 10.3919/jjsa.62.684
• ISSN: 18825133
• ISSN: 13452843
• Web Site: http://www.jstage.jst.go.jp/article/ringe1998/62/3/62_3_684/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2001198221
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可