Preoperative Transcatheter Arterial Chemoembolization(TAE) of Hepatocellular Carcinoma. A Comparative Study.

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  • 肝細胞癌治癒切除例における術前肝動脈塞栓術の評価

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Abstract

To clarify whether preoperative transcatheter arterial chemoembolization (TAE) improves the prognosis and incidence of recurrence in patients with hepatocellular carcinoma (HCC), 49 patients who had undergone curative hepatectomies for HCC were retrospectively examined. These 49 patients were divided into two groups for comparison; 24 patients who underwent preoperative TAE (group A) and 25 patients who did not (group B). No significant differences in outcome were observed between these two groups, except with regard to clinical stage. A significantly more patients in stage II were involved in the group A. Although no significant differences in the survival rate were found between group A and B, the 1, 3 and 5-year cumulative survival rates were 91.1%, 63.9% and 47.3% for group A and 86.3%, 68.0% and 46.6% for group B, respectively. Although no significant differences in the recurrence rate were found between group A and B, the 1, 2 and 3-year tumor-free survival rates were 76.3%, 31.8% and 25.4% for group A and 69.7%, 41.3% and 34.4% for group B, respectively. We suggest that pre-operative TAE is of little help from the standpoint of both recurrence and prognosis and consequently should not be routine procedure for resectable HCC.

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