Production of Antibodies to Sheep Red Blood Cells and Brucella abortus in Mongolian Gerbils (Meriones unguiculatus)

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Author(s)

Abstract

The levels of total and 2-mercaptoethanol (2-ME)-resistant antibodies in male Mongolian gerbils (Meriones unguiculatus) to sheep red blood cells (SRBC) were higher than those in male C57BL/6 mice after the first and second immunizations. On the other hand, the total antibody level to Brucella abortus (BA) in gerbils was comparable to that in mice, whereas 2-ME-resistant antibody titers were lower after the first and second immunizations than in mice. After injection of 8×10<SUP>4</SUP> SRBC, male gerbils did not produce either total or 2-ME-resistant antibodies after the first immunization, but they produced total and 2-ME-resistant antibodies after the first to the fourth immunizations with different dilutions of BA, and both types of antibody titers significantly increased with the repeated immunizations. There were no sex differences in total and 2-ME-resistant antibody production to SRBC.

Journal

  • Experimental Animals

    Experimental Animals 51(2), 163-166, 2002-04

    Japanese Association for Laboratory Animal Science

References:  19

Cited by:  2

Codes

  • NII Article ID (NAID)
    10008394301
  • NII NACSIS-CAT ID (NCID)
    AA11032321
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13411357
  • NDL Article ID
    6136373
  • NDL Source Classification
    ZS7(科学技術--医学)
  • NDL Call No.
    Z54-H752
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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