Circling Mouse, a Spontaneous Mutant in the Inner Ear

Access this Article

Author(s)

    • HONG Sung Hwa
    • Department of ORL-HNS, Samsung Medical Center, Sungkyunkwan University
    • CHUNG Won Ho
    • Department of ORL-HNS, Samsung Medical Center, Sungkyunkwan University
    • LEE Hoon Taek
    • College of Agriculture, Animal and Life Science, Kon-Kuk University
    • CHUNG Kil Saeng
    • College of Agriculture, Animal and Life Science, Kon-Kuk University
    • KIM Tae Yoon
    • Department of Dermatology, Catholic Research Institutes of Medical Science, Catholic Medical College
    • OH Yang Seok
    • Department of Medical Genetics and Experimental Animal Center, College of Medicine, Hallym University
    • SUH Jun Gyo
    • Department of Medical Genetics and Experimental Animal Center, College of Medicine, Hallym University

Abstract

A spontaneous mutant was established in the ICR mouse strain. The affected mice became hyperactive at about 7 days of age, and then showed circling behavior. The body weight decreased significantly 2 weeks after birth, and developmental defects were revealed in the middle ear, cochlea, cochlear nerve, and semicircular canal areas. The mutation was inherited by an autosomal single recessive gene and is referred to as cir.

Journal

  • Experimental Animals

    Experimental Animals 51(2), 167-171, 2002-04

    Japanese Association for Laboratory Animal Science

References:  18

Codes

  • NII Article ID (NAID)
    10008394321
  • NII NACSIS-CAT ID (NCID)
    AA11032321
  • Text Lang
    ENG
  • Article Type
    NOT
  • ISSN
    13411357
  • NDL Article ID
    6136383
  • NDL Source Classification
    ZS7(科学技術--医学)
  • NDL Call No.
    Z54-H752
  • Data Source
    CJP  NDL  J-STAGE 
Page Top