A Hot Water Extract of Adzuki(Vigna angularis) induces Apoptosis in Cultured Human Stomach Cancer Cells.

• Itoh Tomohiro

  Imuraya confectionary Co. Ltd.

• Itoh Yuko

  Imuraya confectionary Co. Ltd.

• Mizutani Mineo

  Imuraya confectionary Co. Ltd.

• Fujishiro Katsuhisa

  Imuraya confectionary Co. Ltd.

• Furuichi Yukio

  Faculty of Bioresources, Mie University

• Komiya Takashi

  Faculty of Bioresources, Mie University

• Hibasami Hiroshige

  Faculty of Medicine, Mie University

Bibliographic Information

Other Title

• ヒト胃癌細胞におけるアズキ熱水抽出物によるアポトーシス誘導
• ヒト イガン サイボウ ニ オケル アズキ ネッスイ チュウシュツブツ ニ ヨル アポトーシス ユウドウ

Abstract

The exposure of human stomach cancer KATO III cells to a hot water extract of adzuki beans led to both growth inhibition and induction of apoptosis (programmed cell death). Morphological changes showing apoptotic bodies were observed in the cells treated with the extract. The fragmentation by the extract of DNA to oligonucleosomal-sized fragments that is a characteristics feature of apoptosis occurred concentration- and time- dependently. These data suggest that the extract of adzuki beans might exert anti-tumor activity by triggering apoptosis.

Journal

• Nippon Shokuhin Kagaku Kogaku Kaishi

  Nippon Shokuhin Kagaku Kogaku Kaishi 49 (5), 339-344, 2002

  Japanese Society for Food Science and Technology

Keywords

• Food Science

Details

• CRID: 1390001206407611008
• NII Article ID: 10008425684
• NII Book ID: AN10467499
• DOI: 10.3136/nskkk.49.339
• ISSN: 18816681
• ISSN: 1341027X
• ISSN: http://id.crossref.org/issn/1341027X
• NDL BIB ID: 6163387
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6163387
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed