蛋白質結晶学におけるシンクロトロン放射光利用の確立  巨大分子用ワイセンベルグシステムの歴史

書誌事項

タイトル別名
  • Establishment of a New Frontier of Protein Crystallography Using SR-X-rays-Development of a Screenless Weissenberg Camera for Macromolecular Crystallography.
  • タンパクシツ ケッショウガク ニ オケル シンクロトロン ホウシャコウ リヨウ ノ カクリツ キョダイブンシヨウ ワイセンベルグ システム ノ レキシ
  • —Development of a Screenless Weissenberg Camera for Macromolecular Crystallography—
  • ―巨大分子用ワイセンベルグシステムの歴史―

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The author and his colleagues have established a new frontier of protein crystallography by developing a novel screenless Weissenberg camera using SR-X-rays at the PF. Luckily, just the first prototype of the camera was being developed, an imaging plate (IP) was also being developed coincidentally for medical use. We combined the camera with IPs and SR-X-rays and established a new data collection system at the PE. This led us to take the initiative of opening this camera system to the worldwide user community of protein crystallographers. Recently, an automated data collection system with fully cylindrical IP-cassettes named Galaxy has been completed based on a totally new idea. Finally time-resolved protein crystallography with monochromatic X-rays and the advanced Galaxy system is discussed.

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