The Mutation in the Mitochondrial Genome of the Out-patients with Hearing Impairment.

• Makishima Tomoko

  Hamanomachi Hospital

• Azuma Kaoru

  Department of Otolaryngology, Kyushu University

• Chujou Kyoko

  Department of Otolaryngology, Kyushu University

• Yamashita Michiko

  Department of Otolaryngology, Kyushu University

• Nakagawa Takashi

  Department of Otolaryngology, Kyushu University

• Komiyama Sotaro

  Department of Otolaryngology, Kyushu University

Bibliographic Information

Other Title

• 外来の難聴患者におけるミトコンドリア遺伝子点変異

Abstract

To search for mutations in mitochondrial genomes among the out-patients with hearing impairment, we investigated the mutations, A1555G, A3243G, A7445G and 7472insC of the mitochondrial genome. Five out of 160 patients, one with the A1555G mutation and four with the A3243G mutation, who comprised approximately 3% of the total patients had a mutation in their mitochondrial genome. The clinical features of these 3 patients are shown.

Journal

• AUDIOLOGY JAPAN

  AUDIOLOGY JAPAN 44 (1), 54-59, 2001

  Japan Audiological Society

Keywords

• ミトコンドリア遺伝子
• 遺伝性難聴
• スクリーニング

Details

• CRID: 1390001204839757440
• NII Article ID: 130003713017
• NII Article ID: 10008449303
• NII Book ID: AN00000347
• DOI: 10.4295/audiology.44.54
• ISSN: 18837301
• ISSN: 03038106
• Web Site: https://search.jamas.or.jp/link/ui/2001253393
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed