Hepatic Role in the Storage and Utilization of Fish Oil Fatty Acids in Humans: Studies on Liver Surgery Patients.

• SEKINE Kohsaku

  the First Department of Internal Medicine, Iwate Medical University School of Medicine

抄録

Fish oil fatty acids (FOFA) were analyzed in fresh liver tissue and in subcutaneous and omental adipose tissue obtained from 5 patients who underwent partial hepatectomy. FOFA were also determined in plasma from 5 patients and in 10 healthy subjects. There was a high content of FOFA in the liver phospholipid (PL) fraction (twice that in our previous autopsy study) suggesting that these surgery patients had a hepatic FOFA content of at least 25g. In plasma, FOFA was predominantly found in the PL of high density lipoprotein (HDL) and partly in the PL of other lipoproteins. Since these lipoproteins are produced by the liver, the present findings indicate the role of the liver not only in storage but also in the utilization of FOFA to form the biologically important surface PL component of circulating lipoproteins.<br>(Internal Medicine 34: 139-143, 1995)

収録刊行物

• Internal Medicine

  Internal Medicine 34 (3), 139-143, 1995

  一般社団法人 日本内科学会

キーワード

• EPA
• DHA
• human liver
• lipoproteins

詳細情報

• CRID: 1390282679843295616
• NII論文ID: 10008450149
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.34.139
• COI: 1:STN:280:ByqA3cnpsVQ%3D
• ISSN: 13497235
• ISSN: 09182918
• PubMed: 7787315
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine1992/34/3/34_3_139/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1995193167
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可