Collagenous Colitis

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Author(s)

    • KATANUMA Akio
    • The First Department of Internal Medicine, Sapporo Medical University
    • TAMAKI Tomohiro
    • The First Department of Internal Medicine, Sapporo Medical University
    • KATABAMI Shigeo
    • The First Department of Internal Medicine, Sapporo Medical University
    • ITOH Jun
    • The Department of Internal Medicine, Muroran City General Hospital
    • IMAI Kouzou
    • The First Department of Internal Medicine, Sapporo Medical University

Abstract

Collagenous colitis is characterized clinically by chronic watery diarrhea and pathologically by colonic mucosal subepithelial collagen deposition. We report a 72-year-old woman who had collagenous colitis associated with chronic watery diarrhea. She received a non-steroidal anti-inflammatory agent (sulindac) because of rheumatoid arthritis. Histological examination of biopsy showed a thick subepithelial collagen layer with lymphocytes, plasma cells, and infiltration of a few eosinocytes in the lamina propria. These findings led to the diagnosis of collagenous colitis. After treatment with salazosulfapyridine, her bowel movement became normalized and mucosal subepithelial collagen deposition disappeared.<br>(Internal Medicine 34: 195-198, 1995)

Journal

  • Internal Medicine

    Internal Medicine 34(3), 195-198, 1995-03-01

    The Japanese Society of Internal Medicine

References:  10

Cited by:  5

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