PTHrP-producing Tumor: Squamous Cell Carcinoma of the Liver Accompanied by Humoral Hypercalcemia of Malignancy, Increased IL-6 and Leukocytosis

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Author(s)

Abstract

A 77-year-old man was admitted to our hospital showing symptoms of general fatigue and appetite loss. He had leukocytosis, thrombocytosis and hypercalcemia with elevated serum levels of parathyroid hormone related peptide (PTHrP) and interIeukin-6 (IL-6). An increase in tumor markers SCC and CYFURA21-1 was observed. The liver contained a huge tumor, which was proved to be PTHrP producing squamous cell carcinoma by immuno-histochemical analysis. Since the tumor did not express IL-6, it was assumed to be induced by PTHrP in osteoblasts. This is the first report of PTHrP producing squamous cell carcinoma of the liver.<br>(Internal Medicine 41: 371-376, 2002)

Journal

  • Internal Medicine

    Internal Medicine 41(5), 371-376, 2002-05-01

    The Japanese Society of Internal Medicine

References:  29

Codes

  • NII Article ID (NAID)
    10008450750
  • NII NACSIS-CAT ID (NCID)
    AA10827774
  • Text Lang
    ENG
  • Article Type
    NOT
  • ISSN
    09182918
  • NDL Article ID
    6169560
  • NDL Source Classification
    ZS21(科学技術--医学--内科学)
  • NDL Call No.
    Z53-M398
  • Data Source
    CJP  NDL  J-STAGE 
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