Primary Hyperparathyroidism with Duodenal Ulcer and H. pylolri Infection

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Author(s)

Abstract

A patient with duodenal ulcer and primary hyperparathyroidism was found to have an abnormally high intragastric pH. The pH level returned to normal after surgical removal of the parathyroid adenoma followed by normalization of parathyroid hormone (PTH) and serum calcium concentrations. The patient was positive for <i>Helicobacter pylori (H. pylori)</i> infection. Although the exact mechanism by which chronic hypercalcemia or high PTH level inhibited gastric acid secretion in this case remains unclear, our findings suggest that hypercalcemia may play some role in <i>H. pylori</i> associated gastroduodenal diseases through induction of proinflammatory cytokines or by enhancing the attachment of <i>H. pylori</i> to gastric epithelial cells.<br>(Intenal Medicine 41: 377-380, 2002)

Journal

  • Internal Medicine

    Internal Medicine 41(5), 377-380, 2002-05-01

    The Japanese Society of Internal Medicine

References:  22

Codes

  • NII Article ID (NAID)
    10008450780
  • NII NACSIS-CAT ID (NCID)
    AA10827774
  • Text Lang
    ENG
  • Article Type
    NOT
  • ISSN
    09182918
  • NDL Article ID
    6169576
  • NDL Source Classification
    ZS21(科学技術--医学--内科学)
  • NDL Call No.
    Z53-M398
  • Data Source
    CJP  NDL  J-STAGE 
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