An Autopsy Case of Amyotrophic Lateral Sclerosis Accompanied by Syndrome of Inappropriate Secretion of Antidiuretic Hormone

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Author(s)

Abstract

We report an autopsy-confirmed case of amyotrophic lateral sclerosis (ALS) accompanied by syndrome of inappropriate secretion of antidiuretic hormone (SIADH). A 67-year-old man was admitted to our hospital with muscle weakness, dysarthria and dysphagia. During hospitalization, respiratory insufficiency was ingravescent, and hyponatremia, hypo-osmolarity, elevated osmotic pressure of urine, and elevated urinary sodium excretion were noted. Based on these findings we diagnosed ALS with SIADH, and treatment with infusion of concentrated NaCl was started. However, the patient died of respiratory failure on day 50. We assumed that severely restrictive ventilatory impairment was the cause of SIADH in this case.<br>(Intrenal Medicine 41: 395-397, 2002)

Journal

  • Internal Medicine

    Internal Medicine 41(5), 395-397, 2002-05-01

    The Japanese Society of Internal Medicine

References:  15

Cited by:  1

  • A case of interstitial pneumonia accompanying SIADH  [in Japanese]

    SONO Koji , KAWASHIMA Tatsuo , MARUYAMA Kozo , ASHIZAWA Misako , KAWASHIMA Sayaka , KIKKAWA Kyoko , NISHI Yumiko , KURODA Toshihisa , GOTO Tsukane , MATUZAWA Yasuo , MATUMURA Ryutaro , SHIRAI Koji

    日本呼吸器学会雑誌 = The journal of the Japanese Respiratory Society 44(3), 178-184, 2006-03-10

    Ichushi Web  References (11) Cited by (2)

Codes

  • NII Article ID (NAID)
    10008450862
  • NII NACSIS-CAT ID (NCID)
    AA10827774
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    09182918
  • NDL Article ID
    6169641
  • NDL Source Classification
    ZS21(科学技術--医学--内科学)
  • NDL Call No.
    Z53-M398
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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