EBCT(electron beam CT)による冠動脈石灰化検出と運動負荷心電図の比較,及び加齢の影響について

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タイトル別名
  • Comparison of Electron Beam Computed Tomography and Exercise Electrocardiography in Detecting Coronary Artery Disease in the Elderly.
  • EBCT electron beam CT ニ ヨル カン ドウミャク セッカ

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Although exercise electrocardiography (ECG) is a useful noninvasive screening test for coronary artery disease (CAD), one prerequisite for ECG screening is that patient be able to exercise enough to evoke myocardial ischemia. Thus, exercise ECG may not be suitable for, some elderly people with CAD who cannot exercise enough. We compared electron beam Computed Tomography (EBCT) with exercise ECG for detecting CAD in 196 patients (mean age, 58.4±12.5 [standard deviation]) who had undergone coronary angiography. Using the angiographic findings as the “gold standard”, we found that the sensitivity, specificity, positive predictive value, and negative predictive value were 88%, 77%, 89%, and 77%, respectively, for EBCT, and 66%, 72%, 83%, and 52%, respectively, for exercise ECG. Although the results were similar when the subjects were divided into different age groups, the negative predictive value for exercise ECG, among older patients was very low. These findings suggest that EBCT is superior to exercise ECG in detecting CAD in the elderly.

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