Aspergillosis Following Influenza A Infection.

• Funabiki Yasuko

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Ishii Kenji

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Kusaka Shigeru

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Hakamata Yasuhiro

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Wakatsuki Yoshio

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Murakami Motonobu

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Yokode Masayuki

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Kume Noriaki

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Horiuchi Hisanori

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

• Kita Toru

  Department of Geriatric Medicine, Faculty of Medicine, Kyoto University

Bibliographic Information

Other Title

• インフルエンザＡ感染症に併発したアスペルギルス症の１例

Abstract

An 83-year-old man had an influenza-like upper respiratory infection that progressed to pneumonia and respiratory insufficiency during a period two weeks. After admission, anti-influenza A antibody increased 32-fold and antibiotic treatment had little effect on the pneumonia. Aspergillus antigen was detected from his serum and pleural effusion, however, culture of sputum was negative for aspergillus. Administration of amphotericin B reduced the serum level of aspergillus antigen, however he died due to the progression of respiratory insufficiency and bloody sputum. Aspergillus infection is generally thought to occur in immunocompromised hosts, but this patient had no apparent immunosuppressive conditions except for his age before the influenza A infection. His WBC and lymphocyte count temporally decreased to 2, 000×10⁶/L (lymphocytes 160×10⁶/L) followed by aspergillus infection. This temporally reduction of lymphocytes is thought to have been responsible for the aspergillus infection. Complications of influenza infection are sometimes fatal and vaccination against influenza seems necessary in high risk individuals such as elderly people.

Journal

• Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics

  Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 36 (4), 274-278, 1999

  The Japan Geriatrics Society

Keywords

• Influenza
• Aspergillus
• Elderly
• Lymphocytopenia

Details

• CRID: 1390001205021841024
• NII Article ID: 130003444409
• NII Article ID: 10008484504
• NII Book ID: AN00199010
• DOI: 10.3143/geriatrics.36.274
• ISSN: 03009173
• PubMed: 10410572
• Web Site: https://search.jamas.or.jp/link/ui/1999250605
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed