胸膜の巨大なsolitary fibrous tumorの1例

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  • A case of giant solitary fibrous tumor of the pleura.

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A 38-year-old woman, who had had sometimes light left back pain, was referred to the hospital because of abnormal shadow on a chest X-ray film at a mass screening. Chest CT scan showed a giant, well-defined, expansive and solid tumor occupied more than half of the left hemithorax. Operative findings revealed that the tumor was extrapulmonarily growing from the visceral pleura of the left S6-10 and involving the pulmonary artery and bronchus. Left pneumonectomy and systematic hilar and mediastinal lymphadenectomy were performed. The tumor measured 21×11×7cm and weighed 1750g. The section was grayish white in color and there was no necrosis nor lymph node metastasis. Histopathologically fibroblast like spindle cell manifested patternless pattern. Immunohistochemically, the tumor was negative for EMA, cytokeratin and S-100, while positive for Vimentin, indicating CD34 negative. These findings were morphologically compatible with solitary fibrous tumor. The postoperative course was uneventful. She is living and well without evidence of relapse, as of 5 years after the operation.

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