後腹膜原発機能性paragangliomaの1治験例  [in Japanese] A CASE REPORTOFFUNCTIONAL RETROPERITONEAL PARAGANGLIOMA  [in Japanese]

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Abstract

paraganglioma(傍神経節腫)は,異所性褐色細胞腫とよばれ,発生学上副腎髄質と同じ由来とされ,カテコラミンを分泌しカテコラミン分泌の有無と臨床症状の有無により機能性と非機能性とに分類される.高血圧を示した.機能性paragangliomaの1治験例を経験したので報告する.<br> 症例は59歳,男性.腹部腫瘤を指摘され来院した腹部超音波検査とCT検査により大きさ約10×10cm,嚢胞状の後腹膜腫瘤と診断された.<br> 腫瘤は,下行結腸を合併切除し,摘出したが,摘出操作により腫瘤内のカテコラミンが血中に逸脱し,術中血圧上昇をきたし,摘出終了と同時に血圧は正常に下降した.<br> 腫瘤内容液よりアドレナリン220ng/ml,ノルアドレナリン87μg/ml, NSE (Neuron specific enolase) 1,200ng/mlが定量された.<br> 組織学的,免疫組織学的にもparagangliomaと診断された.

Paraganglioma is a rare tumor arising from the extraadrenal paraganglion tissues. Paragangliomas can be shown to contain small amount of catecholamines, are designated “functional” or “non-funtional” according to whetehr or not they secrete catecholamines and produce the clinical syndrome of a pheochromocytoma.<br> A 59-year-old man was admitted to the hospital because of a huge abdominal mass. Ultrasonography and computed tomography fo the abdomen revealed a single, large retroperitoneal tumor approximately 10cm in diameter.<br> The tumor was excised with the descending colon. The tumor secreted catecholamines which elevated blood pressure while the operation. The increased level of catecholamines before operation decreased to normal range just after extirpation of the tumor. From a solusion involved in the tumor, 220ng/ml of adrenaline, 87μg/ml of noradrenaline, and 1, 2000ng/ml of neuron specific enolase were quantitatively determined. Histopathologic and immunohistopathologic findings confirmed the paraganglioma.

Journal

  • The journal of the Japanese Practical Surgeon Society

    The journal of the Japanese Practical Surgeon Society 56(3), 640-644, 1995-03-25

    Japan Surgical Association

References:  10

Cited by:  2

Codes

  • NII Article ID (NAID)
    10008512577
  • NII NACSIS-CAT ID (NCID)
    AN00198696
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03869776
  • Data Source
    CJP  CJPref  J-STAGE 
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