同時性肝転移に対し胃癌切除後1年間動注化学療法を行い切除し得た1例

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  • A CASE OF GASTRIC CANCER WITH A SYNCHRONOUS HEPATIC METASTASIS WHICH WAS REMOVED BY SUBSEGMETECTOMY OF THE LIVER AFTER INTRAARTERIAL CHEMOTHERAPY

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A 59-year-old male was diagnosed as to have an advanced gastric cancer with a 1.5×1.2cm solitary liver metastasis. He underwent a gastrectmy with regional lymph node dissection, and an intrahepatic arterial catheter was implanted for the metastatic lesion. After the operation ADM 20mg was given every 2 weeks via the hepatic artery. UFT was given orally in a dose of 600mg/day. One year after the operation, CT scan revealed no growing of the metastatic liver tumor. However, the infusional arterial catheter was obliterated with coagulation of blood and we stopped the arterial chemotherapy. After two months, CT scan revealed a growing of the metastatic liver tumor, but no new metastasis was found. Subsegmentectomy of the liver was performed. Histopathological findings showed the necrosis in the center of the tumor that might be caused by intraarterial chemotherapy. After the second operation, the patient was given CDDP at a dose of 20mg/m2/M intravenously and UFT 400mg/day orally.<br> In this case, intraarterial chemotherapy was effective in controlling the metastatic liver tumor from the stomach cancer.

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