OK-432を用いた進行胃癌術後免疫化学療法の有効性について

• 浅田 康行

  福井県済生会病院外科

• 森田 克哉

  福井県済生会病院外科

• 三浦 将司

  福井県済生会病院外科

• 宗本 義則

  福井県済生会病院外科

• 笠原 善郎

  福井県済生会病院外科

• 齊藤 英夫

  福井県済生会病院外科

• 三井 毅

  福井県済生会病院外科

• 飯田 善郎

  福井県済生会病院外科

• 藤沢 正清

  福井県済生会病院外科

書誌事項

タイトル別名

• RESULTS OF IMMUNOCHEMOSURGERY WITH OK-432 IN ADVANCED GASTRIC CANCER

抄録

In order to evaluate OK-432, a streptococcal preparation, as an postoperative remedy for the advanced gastric cancer, patients under 70 years of age undergoing curative A or B surgery from 1981-1992 were picked up and retrospectively examined.<br> Subjects were 67 patients who received immunochemotherapy using OK-432 (OK-432 group) and 74 receiving chemotherapy alone were served as control (control group). Survival rates were compared between 2 groups by clinicopathological factors. OK-432 group showed significantly better outcomes in curative B surgery (p<0.05), and stage IIIa, b (p<0.01). Pathologically, OK-432 group had significantly better survival rates (p<0.05) in the following factors: se of depth of invasion, diffuse type of Lauren's classification, type 2 of gross appearance, and n₂ of lymp node metastasis. These results suggest OK-432 can be used effectively for patients with advanced gastric cancer after curative B surgery.

収録刊行物

• 日本臨床外科医学会雑誌

  日本臨床外科医学会雑誌 57 (3), 509-516, 1996

  日本臨床外科学会

キーワード

• 胃癌
• 免疫化学療法

詳細情報

• CRID: 1390001205314932992
• NII論文ID: 130003432089
• NII論文ID: 10008519424
• NII書誌ID: AN00198696
• DOI: 10.3919/ringe1963.57.509
• ISSN: 21892075
• ISSN: 03869776
• Web Site: http://www.jstage.jst.go.jp/article/ringe1963/57/3/57_3_509/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1996188982
• データソース種別:
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  • Crossref
  • CiNii Articles
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