Gastric stromal tumorの1例

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  • A CASE OF GASTRIC STROMAL TUMOR

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A 63-year-old man was pointed out an abnormal shadow of the stomach by upper gastrointestinal series at an annual physical examination. He was diagnosed as having a submucosal tumor of the stomach at the department of internal medicine in our hospital. He had been followed up because he was a symptomatic and the size of tumor was less than 2cm. Since histological examination of biopsy specimens offered no certain clue and the tumor was growing rapidly, he was referred to our department and a proximal gastrectomy was performed. The resected specimen showed that the tumor 3cm in diameter existed in the area from submucosal layer to subserosa with well-defined margin. Histopathologically, the tumor was composed of spindle cell proliferation with a thin fibrotic capsule partially. Immunohistochemical study showed that the tumor was negative for smooth muscle antigen (SMA), S-100 protein and so on, but was positive for CD34 only. Therefore it was diagnosed as gastric stromal cell tumor with uncertain origin that represented neither typical leiomyoma nor schwannoma. Mitotic index was 3-5/10 high power field (borderline). The concept of stromal tumors has not been yet established, and so we report this case with literary consideration.

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