^<123>I-IMP SPECTにて逆再分布現象を認めた側頭葉てんかんの2例  [in Japanese] Two Patients with Localization-related Epilepsy Showed Reversed Redistribution on ^<123>I-IMP SPECT  [in Japanese]

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Abstract

<SUP>123</SUP>I-1MP SPECTにて逆再分布現象を示した局在関連性てんかんの2症例を経験した. いずれも発作の数時間後に検査を受けており, 発作コントロールを行って後の検査では逆再分布が認められなかったことから, 逆再分布現象がてんかん原焦点における発作直後のIMPの停滞能の異常を反映している可能性が考えられた.<BR>2症例とも逆再分布現象が生じた部位が発作間欠期頭皮上脳波所見やMRI所見から推測されるてんかん原焦点部位と一致することから, 発作直後の逆再分布現象を利用したてんかん原焦点の局在決定の可能性が示唆された.

Two patients with localization-related epilepsy showed reversed redistributions of <SUP>123</SUP>I-IMP on SPECT examinations which were carried out within a few hours after seizures. Re-examinations in seizure free periods failed to yield the reversed redistribu tions in both patients. It is most probable that a postictal abnormality of the cortical tissue retains IMP at the epileptogenic focus and this IMP retention mechanism reveals the postictal abnormality as reversed redistribution on SPECT.<BR>In either patient, the localization of reversed redistribution was congruent with the epileptogenic focus determined by EEG or MRI findings. It should be useful to carry out <SUP>123</SUP>I-IMP SPECT within a few hours after the seizures to determine the localization of the epileptogenic focus.

Journal

  • Journal of the Japan Epilepsy Society

    Journal of the Japan Epilepsy Society 14(1), 25-30, 1996-02-29

    JAPAN EPILEPSY SOCIETY

References:  14

Codes

  • NII Article ID (NAID)
    10008555605
  • NII NACSIS-CAT ID (NCID)
    AN10043823
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    09120890
  • Data Source
    CJP  J-STAGE 
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