睡眠時に大発作が集積するてんかんと覚醒時に大発作が集積するてんかんの臨床特徴の再検討 : その他の大発作を有するてんかんと比較して  [in Japanese] Clinical Characteristics of Sleep Grand Mal of Janz and Grand Mal on Awakening-A Comparison with Diffuse Grand Mal  [in Japanese]

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Author(s)

    • 川崎 淳 KAWASAKI Jun
    • 国立療養所宇多野病院関西てんかんセンター Kansai Regional Epilepsy Center, Utano National Hospital
    • 河合 逸雄 KAWAI Itsuo
    • 国立療養所宇多野病院関西てんかんセンター Kansai Regional Epilepsy Center, Utano National Hospital

Abstract

睡眠時に大発作が集積して出現する224例のてんかん例と覚醒時に大発作が集積する86例のてんかん例を, 特に時間帯と関係なしに大発作が出現する1, 590例のてんかん例と比較した. その結果, 睡眠時大発作は症候性局在関連てんかんと最も強い関連を示し, 精神性前兆, 脳波上は側頭部焦点が有意に多かった.症候群別では前頭葉てんかんと側頭葉てんかんと有意の関連を示した. 他方, 覚醒時の大発作は特発性全般てんかんと最も強く関連し, 欠神発作, ミオクロニー発作, 3c/sおよびそれより速い全般性棘徐波が有意に多かった. 症候群別では若年性ミオクロニーてんかんと有意の相関を示した. さらに睡眠時大発作てんかんは局在関連てんかん全体の予後と比較すると有意に良好な寛解率を示し, 覚醒時大発作てんかんは特発性全般てんかん全体と比べると有意差には到らないがより良好な寛解率を示した.

This study investigates the histories and the clinical course of 224 patients who had grand mal almost always during sleep (SGM group) and 86 patients who had grand mal on awakening (GMA group). We used 1590 patients who had grand mal and did not belong to neither of the former two groups as a control. We confirmed that the SGM group was strongly related to symptomatic localization-related epilepsy, espe cially temporal and frontal lobe epilepsy and that psychic aura as well as temporal EEG foci occurred significantly more often. In contrast, the GMA group was strongly related to idiopathic generalized epilepsy, especially juvenile myoclonic epilepsy. Absence and generalized myoclonic seizure, together with 3 c/s or faster generalized spike and wave, occurred significantly more often in the GMA group. In agreement with previous reports, the SGM group exhibited a better prognosis in comparison with symptomatic localization-related epilepsy in general.

Journal

  • Journal of the Japan Epilepsy Society

    Journal of the Japan Epilepsy Society 14(3), 181-186, 1996-10-31

    JAPAN EPILEPSY SOCIETY

References:  10

Codes

  • NII Article ID (NAID)
    10008555741
  • NII NACSIS-CAT ID (NCID)
    AN10043823
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    09120890
  • Data Source
    CJP  J-STAGE 
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