一側側頭葉に可逆性のMRI異常信号域を認めた側頭葉てんかんの1例  [in Japanese] A Case of Temporal Lobe Epilepsy with Reversible MRI Lesions Over the Left Anterior Temporal Lobe  [in Japanese]

Access this Article

Search this Article

Author(s)

Abstract

頭部MRIにて可逆性のT1低、T2、FLAIR高信号域を呈した56歳のてんかん患者を報告する。本例はてんかん発作初発の半年後より、右眼瞼、口角、上下肢の瞬時の痙攣、脱力、発語停止など焦点発作、意識減損発作が目立つようになった。発作頻度の増加に平行して記銘力障害が悪化、MRIにて左側海馬萎縮、同側側頭葉前部の異常信号域が認められた。脳波では左蝶型骨誘導に限局した棘波を認めた。抗てんかん薬投与後、発作はほぼ消失、異常信号域も消退した。一方、記銘力障害、海馬萎縮は持続した。複雑部分発作重積後に頭部MRIで限局性異常信号域をみることが報告されている。本症例から、重積でなく短い発作の反復によっても異常信号域を生じ得ると考えられた。

We reported a case of 56 year-old right-handed man who presented reversible low T1-weighted, high T2-weighted and FLAIR signal intensity lesion over the left anterior temporal lobe with hippocampal atrophy on the same side. His epileptic symptoms were characterized by focal seizures such as twitching of the right facial muscles, vocal arrest, tonic convulsion or atonic attacks of the right limbs. He also presented disturbance of recent memory. Electroencephalogram revealed focal spike activities restricted to the left sphenoidal lead. The abnormal signal lesion on MRI disappeared almost completely in three months after the beginning of medication leaving a marked atrophy of the left hippocampus with the recent memory disturbance remaining unchanged. Several reports mention that reversible abnormal signal lesion on MRI often occurs after status epileptics. Our patient indicates that less frequent focal seizures and/or paroxysmal electrical discharges can also cause this lesion.

Journal

  • Journal of the Japan Epilepsy Society

    Journal of the Japan Epilepsy Society 19(1), 17-23, 2001-02-28

    JAPAN EPILEPSY SOCIETY

References:  20

Codes

  • NII Article ID (NAID)
    10008556369
  • NII NACSIS-CAT ID (NCID)
    AN10043823
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    09120890
  • Data Source
    CJP  J-STAGE 
Page Top