タバコ煙暴露で増加する血漿化学発光の特性  [in Japanese] Characteristics of Plasma Low-level Chemiluminescence upon Stimulation with Cigarette Smoke  [in Japanese]

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Author(s)

Abstract

タバコ煙暴露で増加する血漿化学発光の性質を, ラットとマウスを用いて調べた。ラットにタバコ煙を3分間暴露すると, 20分後には血漿化学発光が暴露前の約3倍に著増し, その後減衰して, 暴露80分後には暴露前の値にまで低下した。このタバコ煙依存の血漿化学発光は, 500~580nmに極大発光を示し, タバコ中のタール含量とは相関しなかった。α-カロチンおよびβ-カロチンの経口投与はこの血漿化学発光に影響を与えなかったが, スルフヒドリル化合物であるシステインやグルタチオンを血漿に添加すると発光は抑制された。

The characteristics of plasma low-level chemiluminescence upon stimulation by exposure to cigarette smoke were studied. When rats were exposed to cigarette smoke for 3min, the plasma chemiluminescence after 20min showed a significant increase of about 3-fold compared with that in control rats, and the chemiluminescence decayed to the control level after 80min. The plasma chemiluminescence upon enhancement with cigarette smoke had maximum emission bands around 500-580nm, and the intensity was not dependent on the tar content of the cigarettes. Oral intake of carotenes had no effect, but plasma supplementation with sulfhydryl compounds such as cysteine and glutathione suppressed the cigarette smokeinduced chemiluminescence.

Journal

  • Nippon Eiyo Shokuryo Gakkaishi

    Nippon Eiyo Shokuryo Gakkaishi 48(2), 115-120, 1995-04-10

    Japan Society of Nutrition and Food Science

References:  24

Codes

  • NII Article ID (NAID)
    10008561764
  • NII NACSIS-CAT ID (NCID)
    AN00311992
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    02873516
  • NDL Article ID
    3619040
  • NDL Source Classification
    SC221(衛生学・公衆衛生)
  • NDL Source Classification
    ZS8(科学技術--医学--解剖学・生理学・生化学)
  • NDL Call No.
    Z19-53
  • Data Source
    CJP  NDL  J-STAGE 
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