Effect of Extracts form Hovenia dulcis Thunb. on Alcohol Concentration in Rats and Men Administered Alcohol.

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  • アルコールを投与されたラットおよびヒトのアルコール濃度に及ぼすケンポナシ(Hovenia dulcis Thunb.)抽出物の影響
  • アルコール オ トウヨサレタ ラット オヨビ ヒト ノ アルコール ノウド ニ

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Abstract

The effect of extracts from Hovenia dulcis Thunb. on alcohol (ethanol) concentration after administration of alcohol to rats and men were examined. When a fraction (Fr. G, 0.5g/kg b. w.) extracted from H. dulcis was administered orally to rats 5min before oral administration of alcohol (2g/kg b. w.), the percentage decreases in maximum blood alcohol and acetaldehyde levels were 40% and 37%, respectively, the decreases being larger than those induced by other fractions from H. dulcis. On the other hand, when ethanol extract (0.125g/kg b. w.) was administered orally to men 20min before oral administration of alcohol (0.3g/kg b. w.), decreases in alcohol and acetaldehyde concentrations in saliva were observed, and the expiratory alcohol concentration at 1h after drinking beer was significantly decreased in five men out of eight

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