仔ラットの肝臓と大脳皮質脂質および脂肪酸組成に及ぼす泌乳期ラットのドコサヘキサエン酸エチルエステル摂取の影響  [in Japanese] Effect of Docosahexaenoic Acid Ethyl Ester Supplement for Lactating Rat on Lipid and Fatty Acid Compositions of Pup's Liver and Cerebral Cortex  [in Japanese]

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Abstract

ウィスター系雌ラットを大豆油を含む飼料で飼育し, 出産後大豆油食とDHAエチルエステル添加食に分けた。<BR>1) 仔ラットの胃から採取した乳汁の22: 6n-3濃度は, 大豆油群では初乳で最大値を示した後にしだいに減少したが, DHA食群ではしだいに増加した。<BR>2) 肝臓トリグリセリドの22: 6n-3濃度は5日齢で最大値 (大豆油食群, 4.5%; DHA食群, 13.1%) を示した。また, 各年齢で, 大豆油食群よりDHA食群の値が高かった。<BR>3) 肝臓リン脂質の22: 6n-3濃度は, 大豆油群では5日齢で最大値を (15.6%), DHA食群では5~20日齢の範囲で高値 (17.4~19.2%) を示した後に減少した。また, 各年齢で大豆油群よりDHA食群の値が高かった。<BR>4) 大脳皮質リン脂質の22: 6n-3濃度は成熟ラットでの値が最も高かった (大豆油食群, 17.8%; DHA食群, 19.7%)。また, 大豆油食群よりDHA食群が高値を示したが, その差は20日齢において最も顕著であった (大豆油食群, 14.1%; DHA食群, 16.7%)。

Female Wistar rats which had been fed a diet containing soy bean oil (soya) for 4 weeks before mating were divided into two dietary groups after delivery: half of the rats were fed a diet supplemented with docosahexaenoic acid ethyl ester (DHA), and the other half were kept on the soy bean oil diet. Weaned rats were fed the same diet that had been given to their mothers. The fatty acid composition of milk obtained from the stomachs of pups, and also that of the liver and cerebral cortex was analyzed. During lactation, the DHA level in milk was higher in the DHA group than in the soya group. The DHA levels in both the liver and cerebral cortex were also higher in the DHA group than in the soya group. However, the DHA levels in the cerebral cortex of the two groups were approximately the same in both weaned and adult rats. DHA intake was more effective in elevating the concentration of DHA in the liver and cerebral cortex of suckling pups than in weanling pups.

Journal

  • Nippon Eiyo Shokuryo Gakkaishi

    Nippon Eiyo Shokuryo Gakkaishi 48(3), 173-180, 1995-06-10

    Japan Society of Nutrition and Food Science

References:  19

Cited by:  4

Codes

  • NII Article ID (NAID)
    10008562434
  • NII NACSIS-CAT ID (NCID)
    AN00311992
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    02873516
  • NDL Article ID
    3619213
  • NDL Source Classification
    SC226(衛生学・公衆衛生--食品衛生・栄養学)
  • NDL Source Classification
    ZS8(科学技術--医学--解剖学・生理学・生化学)
  • NDL Call No.
    Z19-53
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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