成長期ラットにおけるカゼインホスホペプチド (CPP) 中のカルシウムおよびリンの利用性  [in Japanese] Availability of Calcium (Ca) and Phosphorus (P) from Casein Phosphopeptides (CPP) in Growing Rats  [in Japanese]

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Author(s)

Abstract

Ca, P源としてのCPPに着目し, 飼料中の80%のCaとすべてのPをCPPにより補給した飼料 (飼料Ca水準, 0.5%: P水準, 0.4%) を用い, CaとPの利用性について検討を行った。その結果, 雄ラットではCPP食群のCaの吸収率と保持量は対照群よりも高値であった。雌ラットではCaの吸収率と保持量でCPP食群と対照食群との間に差がみられなかった。雌雄それぞれにおいてCPP食群のP吸収率と保持量が高く, CPP中に含まれるPの体内利用性は, 無機リンと比較して高いことが示唆された。また, 雌雄それぞれにおいてMg吸収率が高かった。CPPの摂取による腎組織中ミネラル量の増加や血清ミネラル上昇はみられなかった。以上のことからCPPに由来するP, Caの利用性は良好であることが示唆された。

Casein phosphopeptides (CPP) enhance the absorption of calcium (Ca) by inhibiting the precipitation of calcium phosphate in vitro, although the effect on in vivo balance is controversial. This study was undertaken to determine the utilization of Ca and phosphorus (P) from CPP itself in growing male and female rats. CPP prepared from a tryptic hydrolysate of whole casein was added to a test diet, 80% of dietary Ca and 100% of dietary P being supplied as CPP. The dietary Ca and P levels were 5g/kg and 4g/kg, respectively. During the 23-day feeding period, a mineral balance study was carried out from days 19 to 22. The apparent Ca, P and magnesium (Mg) absorption rate, and Ca and P retention in the male rats fed the CPP diet were significantly higher than the equivalent values in the male rats fed with control diet (p<0.05). There was no significant difference in apparent Mg retention among the male groups. The apparent P absorption rate, P retention, and Mg absorption rate in the female rats fed the CPP diet w re significantly higher than the equivalent values in the female rats fed the control diet (p<0.05). There was no significant difference in the apparent Ca absorption rate, Ca retention, and Mg retention among the female groups. No significant difference was observed between the CPP diet group and the control diet group with regard to the mineral contents of the serum and kidney. It is suggested that Ca and P from CPP could be well utilized in growing rats.

Journal

  • Nippon Eiyo Shokuryo Gakkaishi

    Nippon Eiyo Shokuryo Gakkaishi 48(3), 195-202, 1995-06-10

    Japan Society of Nutrition and Food Science

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Codes

  • NII Article ID (NAID)
    10008562501
  • NII NACSIS-CAT ID (NCID)
    AN00311992
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    02873516
  • NDL Article ID
    3619216
  • NDL Source Classification
    SC226(衛生学・公衆衛生--食品衛生・栄養学)
  • NDL Source Classification
    ZS8(科学技術--医学--解剖学・生理学・生化学)
  • NDL Call No.
    Z19-53
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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