The Cytological and Immunohistochemical Study of Septal Cells in the Rat Lung.

• Aoki Takeo

  Department of Anatomy, Gunma University School of Medicine

• Taira Kazuo

  Department of Anatomy, Gunma University School of Medicine

• Shibasaki Susumu

  Department of Anatomy, Gunma University School of Medicine

• Fujimoto Toyoshi

  Department of Anatomy, Gunma University School of Medicine

抄録

Septal cells in the alveolar interstitium of the lung have been assumed to be contractile and involved in the regulation of ventilation/perfusion ratio. We studied two cytoskeletal components of the septal cell in the rat lung. One contains thick microfilament bundles: by decoration with heavy meromyosin, the bundle was shown to be composed of actin filaments of opposite polarity. The other contains intermediate filaments: by pre-and post-embedding immunogold electron microscopy, they were shown to contain both desmin and vimentin. Double labeling immunoelectron microscopy further revealed that some intermediate filaments are co-polymers of desmin and vimentin. The features revealed in the present study support the hypothesis that septal cells can contract and change the architecture of the air-blood barrier.

収録刊行物

• Ａｃｔａ　Ｈｉｓｔｏｃｈｅｍｉｃａ　ｅｔ　Ｃｙｔｏｃｈｅｍｉｃａ

  Ａｃｔａ　Ｈｉｓｔｏｃｈｅｍｉｃａ　ｅｔ　Ｃｙｔｏｃｈｅｍｉｃａ 28 (4), 349-355, 1995

  日本組織細胞化学会

キーワード

• Immunoelectron microscopy
• Lung
• Septal cell
• Intermediate filament
• Desmin
• Vimentin

詳細情報

• CRID: 1390001204862750976
• NII論文ID: 10008604223
• NII書誌ID: AA00508022
• DOI: 10.1267/ahc.28.349
• ISSN: 13475800
• ISSN: 00445991
• Web Site: http://www.jstage.jst.go.jp/article/ahc1968/28/4/28_4_349/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1996161490
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可