Multi-color FISH : Application to the Simultaneous Detection of Chromosome Aberrations in Neuro-epithelial Tumor Cell Lines

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Author(s)

    • INAZAWA Johji
    • Department of Hygiene, Kyoto Prefectural University of Medicine
    • HOURI Takashi
    • Department of Neurosurgery, Kyoto Prefectural University of Medicine
    • UEDA Satoshi
    • Department of Neurosurgery, Kyoto Prefectural University of Medicine
    • ABE Tatsuo
    • Department of Hygiene, Kyoto Prefectural University of Medicine

Abstract

Fluorescence <I>in situ</I> hybridization (FISH) with chromosome-specific DNA probes allows cytogenetic information to be obtained rapidly and precisely from metaphase and interphase chromosomes. Multi-color FISH with two or more probes makes it feasible to delineate several chromosome aberrations simultaneously occurring in a nucleus. Here we present a simple and rapid method for multi-color FISH and its application to the cytogenetic investigation of tumor cells. In addition, the usefulness of this method is discussed.

Journal

  • ACTA HISTOCHEMICA ET CYTOCHEMICA

    ACTA HISTOCHEMICA ET CYTOCHEMICA 28(6), 569-573, 1995-12-01

    JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY

References:  23

Codes

  • NII Article ID (NAID)
    10008604876
  • NII NACSIS-CAT ID (NCID)
    AA00508022
  • Text Lang
    ENG
  • Article Type
    REV
  • ISSN
    00445991
  • Data Source
    CJP  J-STAGE 
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