-
- Suzuki Keiji
- Department of Pathology, College of Medical Care and Technology, Gunma University
-
- Kawashima Kenji
- Department of Pathology, College of Medical Care and Technology, Gunma University
-
- Nakajima Katsuyuki
- Japan Immunoresearch Laboratories
-
- Otaki Nakajima
- National Institute of Industrial Health
-
- Kimura Masami
- School of Medicine, Keio University
-
- Oyama Tetsuya
- Second Department of Pathology, School of Medicine, Gunma University
-
- Takatama Masamitsu
- Geriatrics Research Institute
この論文をさがす
抄録
The localization of the low-molecular-weight heavy-metal-binding protein metallothionein (MT) in the thyroid gland and medullary thyroid carcinoma was investigated by an immunohistochemical technique, and the amount of MT in the thyroid gland was assayed by radioimmunoassay.<BR>MT was immunohistochemically identified in epithelial cells of follicular and parafollicular cells. Both the cytoplasm and the nuclei of the cells stained positive for MT. The nuclear staining for MT was strong. The follicular epithelial cells and colloid were positive for thyroglobulin, and the parafollicular cells were strongly positive for calcitonin.<BR>Medullary thyroid carcinoma was strongly positive for calcitonin, but most tumor cells were negative for MT. MT-positive cells in the tumor were sporadic, and both their nucleus and cytoplasm stained positive.<BR>Radioimmunoassay revealed high levels of MT in the thyroid gland, about 148.7±45.0 μg/g wet weight.
収録刊行物
-
- Ａｃｔａ Ｈｉｓｔｏｃｈｅｍｉｃａ ｅｔ Ｃｙｔｏｃｈｅｍｉｃａ
-
Ａｃｔａ Ｈｉｓｔｏｃｈｅｍｉｃａ ｅｔ Ｃｙｔｏｃｈｅｍｉｃａ 29 (1), 39-43, 1996
日本組織細胞化学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679839275008
-
- NII論文ID
- 10008605109
-
- NII書誌ID
- AA00508022
-
- COI
- 1:CAS:528:DyaK28XkvFKlsbs%3D
-
- ISSN
- 13475800
- 00445991
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可