Apoptosis with DNA Fragmentation in Bowen's Disease and Szuamous Cell Carcinoma

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Author(s)

    • GUO Zaipei
    • Department of Dermatology, Faculty of Medicine, Kyoto University
    • YONEDA Kozo
    • Department of Dermatology, Faculty of Medicine, Kyoto University
    • IMAMURA Sadao
    • Department of Dermatology, Faculty of Medicine, Kyoto University

Abstract

The clinical phenotypes of Bowen's disease and squamous cell carcinoma (SCC) are very different although the origins of these tumors are epidermal keratinocytes. Here we compared the degree of apoptosis in Bowen's disease and squamous cell carcinoma. In Bowen's disease, several individual tumor cells showed apoptosis. In contrast, apoptosis was not found at the tumor mass where the atypical epidermal cells invaded into the dermis in cases of Bowen's carcinoma and squamous cell carcinoma. The possible molecular mechanisms underlying different behaviors of Bowen's disease and SCC are also discussed.

Journal

  • ACTA HISTOCHEMICA ET CYTOCHEMICA

    ACTA HISTOCHEMICA ET CYTOCHEMICA 29(3), 261-263, 1996-06-01

    JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY

References:  6

Codes

  • NII Article ID (NAID)
    10008605639
  • NII NACSIS-CAT ID (NCID)
    AA00508022
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    00445991
  • DOI
    10.1267/ahc.29.261
  • Data Source
    CJP  J-STAGE 
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