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- Kurokawa Kiyoshi
- Department of Anatomy, Shiga University of Medical Science
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- Yamada Hisao
- Department of Anatomy, Shiga University of Medical Science
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- Ochi Junzo
- Department of Anatomy, Shiga University of Medical Science
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The expression of c-fos was analyzed immunohistochemically after injection of endothelin isopeptide into cerebroventricle of the rat. The c-Fos immunoreactivity increased and reached the peak at 1 hr-1.5 hr after the administration of endothelin. Endothelin-1 and endothelin-2 specifically induced c-foss expression in the neurons of paraventricular, supraoptic and periven-tricular nuclei and zona incerta. Endothelin-3 induced c-Fos in the organum vasculosum laminae terminalis in addition to those regions. In these areas, the number of c-Fos-positive neurons increased with a dose (Oto 100 pg of ET) dependent manner. We presume that they are the targeting neurons of central nervous endothelins (ETs).
収録刊行物
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- Acta Histochemica et Cytochemica
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Acta Histochemica et Cytochemica 30 (1), 51-56, 1997
日本組織細胞化学会
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詳細情報
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- CRID
- 1390282679838673280
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- NII論文ID
- 10008606054
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- NII書誌ID
- AA00508022
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- COI
- 1:CAS:528:DyaK2sXjtV2itrY%3D
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- ISSN
- 13475800
- 00445991
- http://id.crossref.org/issn/00445991
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可