GLUT1 Glucose Transporter in the Lactating Mammary Gland in the Rat

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Author(s)

    • TAKATA Kuniaki
    • Laboratory of Molecular and Cellular Morphology, Institute for Molecular and Cellular Regulation, Gunma University,
    • FUJIKURA Keiko
    • Laboratory of Molecular and Cellular Morphology, Institute for Molecular and Cellular Regulation, Gunma University,
    • SUZUKI Masakazu
    • Laboratory of Molecular and Cellular Morphology, Institute for Molecular and Cellular Regulation, Gunma University,
    • SUZUKI Takeshi
    • Laboratory of Molecular and Cellular Morphology, Institute for Molecular and Cellular Regulation, Gunma University,

Abstract

Localization of facilitated-diffusion glucose transporter GLUT1 was examined in the rat mammary gland by immunofluorescence microscopy and immunoperoxidase electron microscopy. Secretory epithelial cells of acini were enriched with GLUT1, which was localized to the basolateral plasma membrane. Apical plasma membrane and cytoplasmic organelles including the Golgi apparatus were negative for GLUT1. In addition to acini, abundant GLUT1 was found in the perineurium of nerve fiber bundles, which is a site of blood-nerve barriers. GLUT1 in the basolateral membrane of secretory epithelial cells seems to serve as machinery to take up glucose into the cell for milk synthesis and secretion.

Journal

  • ACTA HISTOCHEMICA ET CYTOCHEMICA

    ACTA HISTOCHEMICA ET CYTOCHEMICA 30(5), 623-628, 1997-10-01

    JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY

References:  29

Cited by:  2

Codes

  • NII Article ID (NAID)
    10008608080
  • NII NACSIS-CAT ID (NCID)
    AA00508022
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    00445991
  • Data Source
    CJP  CJPref  J-STAGE 
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