書誌事項
- タイトル別名
-
- Clinicopathologic and immunohistochemical study of gastrointestinal stromal tumors (GIST).
この論文をさがす
抄録
We clinicopathologically and immunohistochemically analyzed 30 patients with gastrointestinal stromal tumors (GIST) resected at our department to determine the clinical significance of GIST. Malignant potential was evaluated by tumor size and histopathological findings. Immunohistochemical classification as smooth muscle, neural, combined smooth muscle and neural, and noncommittal evaluated using α-SMA, S-100, CD34, and c-kits. Four patients suffering metastasis or recurrence had large malignant GISTs growing to the extralumen with ulcer formation and central bleeding. Three with GISTs originating in the small intestine died of peritoneal or liver metastasis. Multivariate analysis indicated that the significant prognostic factor was tumor size not immunohistochemical classification, is why the difficulty in diagnosing large GISTs causes poor prognosis. Potential consequences using macroscopic findings, including tumor size, must thus be used in addition to histopathological malignant potential rather than immunohistochemical classification.
収録刊行物
-
- 日本臨床外科学会雑誌
-
日本臨床外科学会雑誌 63 (4), 828-833, 2002
日本臨床外科学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679821708928
-
- NII論文ID
- 130003602941
- 10008618676
-
- NII書誌ID
- AA11189709
-
- ISSN
- 18825133
- 13452843
- http://id.crossref.org/issn/13452843
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可