A recursive procedure to compute the gametic relationship matrix and its inverse for marked QTL clusters

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Abstract

Recently, a variety of mixed linear models have been proposed for marker-assisted prediction of the effects of quantitative trait loci (QTLs) in outbred populations of animals. One of them addresses the effects of a cluster of linked QTLs, or those of a particular chromosomal segment, marked by DNA marker(s) and requires that the inverse of the corresponding gametic relationship matrix whose elements are the conditional expected values of the identity-by-descent (IBD) proportions between gametes for individuals be evaluated. Here, for a model of this type, utilizing the property of the IBD set and using the information on the joint gametogenesis processes at the flanking marker loci, we present a recursive method to systematically calculate the elements of the gametic relationship matrix and its inverse. A numerical example is given to illustrate the proposed computing procedure.<br>

Journal

  • Genes & Genetic Systems

    Genes & Genetic Systems 77(2), 123-130, 2002-04-01

    The Genetics Society of Japan

References:  39

Codes

  • NII Article ID (NAID)
    10008639572
  • NII NACSIS-CAT ID (NCID)
    AA11077421
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    13417568
  • NDL Article ID
    6264869
  • NDL Call No.
    Z53-W539
  • Data Source
    CJP  NDL  J-STAGE 
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