ビルトイン補酵素をもつアミン脱水素酵素の構造研究-新規キノン補酵素と異常な分子内架橋-  [in Japanese] Structural Studies on Quinohemoprotein Amine Dehydrogenase : a Novel Quinonoid Cofactor and Multiple lntramolecular Cross-Bridges  [in Japanese]

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Author(s)

Abstract

Quinohemoprotein amine dehydrogenase (QH-AmDH) from <I>Pseudomonas putida</I> has an αβγ heterotrimeric structure with two heme <I>c</I> groups in the largest α subunit and an unidentified quinone prosthetic group in the smallest γ subunit.<BR>The crystal structure of QH-AmDH has been determined at 1.9Åresolution. This revealed a unique feature of the catalytic γ subunit with a novel cofactor cysteine tryptophylquinone (CTQ) and three intra-chain cross-links. These links are unprecedented as they are thio-ether bonds between a sulfur atom of Cys and a methylene carbon atom of an Asp or a Glu.

Journal

  • Nihon Kessho Gakkaishi

    Nihon Kessho Gakkaishi 44(3), 176-181, 2002-06-28

    The Crystallographic Society of Japan

References:  30

Codes

  • NII Article ID (NAID)
    10008687379
  • NII NACSIS-CAT ID (NCID)
    AN00188364
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    03694585
  • NDL Article ID
    6199834
  • NDL Source Classification
    ZM46(科学技術--地球科学--岩石・鉱物・鉱床)
  • NDL Call No.
    Z15-138
  • Data Source
    CJP  NDL  J-STAGE 
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