Effects of space environment on embryonic growth up to hatching of salamander eggs fertilized and develOped during orbital flights

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Author(s)

    • Bautz Alain [他] BAUTZ Alain
    • Laboratory of Experimental Biology-Immunology, EA 3442: Genetic, Signaling, Differentiation, Henri Poincare Unrversrty Nancy-1
    • DURAND Danielle
    • Laboratory of Experimental Biology-Immunology, EA 3442: Genetic, Signaling, Differentiation, Henri Poincare Unrversrty Nancy-1
    • KAN Paulette
    • Center of Developmental Biology UMR 5547 CNRS- Paul Sabatier University
    • AIMAR Christian
    • Laboratory of Experimental Biology-Immunology, EA 3442: Genetic, Signaling, Differentiation, Henri Poincare Unrversrty Nancy-1
    • MEMBRE Herve
    • Laboratory of Experimental Biology-Immunology, EA 3442: Genetic, Signaling, Differentiation, Henri Poincare Unrversrty Nancy-1
    • DOURNON Christian
    • Henri Poincare University -Nancy-1, B.P. 239, 54506 Vandoeuvre-les-Nancy cedex, France

Abstract

In vertebrates, only few experiments have been performed in microgravity to study the embryonic development from fertilization. To date, these concern only amphibian and fish. We report here a study on the embryonic development of <i>Pleurodeles waltl</i> (urodele amphibian) eggs oviposited in microgravity. The experiment was performed twice on board the Mir space station and the data obtained included video recording and morphological, histological and immunocytological analyses. The data confirm that the microgravity conditions have effects during the embryonic period, particularly during cleavage and neurulation, inducing irregular segmentation and abnormal closure of the neural tube. Moreover, we observed several abnormalities hither to undescribed corresponding to cortical cytoplasm movements, a decrease of cell adhesion and a loss of cells. These abnormalities were temporary and subsequently reversible. The young larvae that hatched during the flight displayed normal morphology and swimming behavior after landing. The results obtained in the urodele <i>Pleurodeles waltl</i> are in accordance with those observed earlier in the anuran <i>Xenopus laevis</i> and in the fish <i>Oryzias latipes</i>.

Journal

  • Biological Sciences in Space

    Biological Sciences in Space 16(1), 3-11, 2002-03-01

    Japanese Society for Biological Sciences in Space

References:  27

Codes

  • NII Article ID (NAID)
    10008690333
  • NII NACSIS-CAT ID (NCID)
    AN10164806
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    09149201
  • NDL Article ID
    6193435
  • NDL Source Classification
    ZR1(科学技術--生物学) // ZM33(科学技術--宇宙科学)
  • NDL Call No.
    Z18-2504
  • Data Source
    CJP  NDL  J-STAGE 
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