A case of subcutaneous and mesenteric acute panniculitis with Sjoegren's syndrome.
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- Sugihara Takahiko
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Koike Rhuji
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Nosaka Yurika
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Ogawa Jun
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Hagiyama Hiroyuki
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Nagasaka Kenji
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Nonomura Yoshinori
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Nishio Junko
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Nanki Toshihiro
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Kohsaka Hitoshi
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Kubota Tetsuo
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
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- Miyasaka Nobuyuki
- Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University
Bibliographic Information
- Other Title
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- 皮下および腸間膜に急性脂肪織炎を伴ったシェーグレン症候群の1例
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Abstract
We report a case of a 27-year-old Japanese female with Sjögren's syndrome (SS), who suffered from several episodes of subcutaneous and mesenteric panniculitis with a recurrence within one year. After a history of fever and skin rash, the patient underwent surgery at a local hospital with a diagnosis of acute appendicitis complicated with an ileocecal abscess. She was also diagnosed as having SS. After the operation, the fever and skin rash persisted. She was treated with prednisolone (PSL), and her symptoms resolved. A recurrent bout of abdominal pain with fever, annular erythema on the trunk and a nodular erythematous rash on the lower extremities occurred six months after the operation. A skin biopsy from the lower extremities showed findings that were compatible with panniculitis. Abdominal computer tomography (CT) showed a diffuse swelling with soft tissue density in the intestinal mesenterium and para-aortic area. A retrospective examination of the operative specimen obtained from the local hospital revealed centrilobular infiltration of neutrophils in the mesenteric adipose tissue with fat necrosis, which is compatible with mesenteric panniculitis. Twenty mg/day of PSL was successful in treating the systemic panniculitis, and the abnormal diffuse soft tissue density on the abdominal CT disappeared after three weeks of PSL administration. Systemic panniculitis is a rare complication in SS, and the pathogenesis is unclear.
Journal
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- Japanese Journal of Clinical Immunology
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Japanese Journal of Clinical Immunology 25 (3), 277-284, 2002
The Japan Society for Clinical Immunology
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Details
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- CRID
- 1390001204649004800
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- NII Article ID
- 10008694556
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- NII Book ID
- AN00357971
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- ISSN
- 13497413
- 09114300
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed