藩種性Fusarium solani感染症を合併したPh^1陽性急性リンパ芽球性白血病の1剖検例 [in Japanese] An Autopsy Case of Ph^1-Positive Acute Lymphoblaxic Leukemia with Disseminated Infection of Fusarium solani [in Japanese]
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A 56-year-old woman with Ph<SUP>1</SUP>-Positive acute Lymphoblastic Leukemia was admitted to our hospital for induction chemotherapy in June 1999. The patient was presented with a central scotoma of left eye during treatment course and was given diagnosis of endophthalmitis . Thereafter she also developed skin induration and suffered from serious pneumonia.<BR>Amphotericin B administration was started because of high titer of β-D-glucan, but soon discontinued due to its adverse effect. Blood cultures yielded colonies of fungus and it was identified <I>Fusarium solani</I>. Her general condition deteriorated with progression of pneumonia, and she died of respiratory insufficiency. Autopsy was performed, and its specimen revealed the disseminated infection of <I>Fusarium solani</I> (lung, eye, heart, kidney and skin).<BR>We should pay special attention to the fusariosis in Japan also.
- Kansenshogaku Zasshi
Kansenshogaku Zasshi 76(1), 67-71, 2002-01-20
The Japanese Association for Infectious Diseases