The Trend of Childhood Bacterial Meningitis in Japan (1997.7-2000.6)
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- SUNAKAWA Keisuke
- Dep. of Infectious Diseases. Kitasato Univ. School of Med.
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- NONOYAMA Masato
- Dep. of Infectious Diseases. Kitasato Univ. School of Med.
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- TAKAYAMA Youko
- Dep. of Infectious Diseases. Kitasato Univ. School of Med.
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- YAMAGUCHI Yoshio
- Dep. of Infectious Diseases. Kitasato Univ. School of Med.
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- OOISHI Tomohiro
- Dep. of Infectious Diseases. Kitasato Univ. School of Med.
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- IWATA Satoshi
- Department of Pediatrics, National Tokyo Medical Center
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- AKITA Hironobu
- Department of Pediatrics, St. Marianna Univercity School of Medicine Yokohama City Seibu Hospital
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- SATO Yoshitake
- Department of Pediatrics, Fuji Heavy Industried Ltd Health Insurance Society General Ota Hospital
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- UBUKATA Kimiko
- Center for Epidemiology&Clinical MIcrobiology, Pharmaceutical Reseach Center, Meiji Seika Kaisha. LTD.
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- CHIBA Nahoko
- Center for Epidemiology&Clinical MIcrobiology, Pharmaceutical Reseach Center, Meiji Seika Kaisha. LTD.
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- HASEGAWA Keiko
- Center for Epidemiology&Clinical MIcrobiology, Pharmaceutical Reseach Center, Meiji Seika Kaisha. LTD.
Bibliographic Information
- Other Title
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- 本邦における1997年7月以降3年間の小児化膿性髄膜炎の動向
- ホンポウ ニ オケル 1997ネン 7ガツ イコウ 3ネンカン ノ ショウニ カノウセイ ズイマクエン ノ ドウコウ
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Abstract
We surveyed the epidemiology of purulent meningitis in pediatrics for 3 years between July 1997 and June 2000 in Japan and obtained the following results. The number of cases of purulent meningitis was 428, which was equivalent to 1.1-1.7 children out of 1, 000 hospitalized those in pediatrics per year. The age-distribution for the infections was the highest under 1 year of age and it decreased as the age increased. Under 1 year of age, the highest distribution was observed in one month of age and under 1 month of age, the highest distribution was observed in 7 days of or younger ages. Haemophilus influenzae was the most common pathogen causing the infections, followed by Streptococcus pneumoniae, group B streptococcus, and Escherichia coli. Relationship betweencausing pathogens and age-distribution was as follows: group B streptococcus and E. coli were major pathogens under 4 months of age and H. influenzae and S. pneumoniae were major pathogens over 3 months of age. Susceptibility tests performed at each facility demonstrated that 25.3% of H. influenzae isolates and 38.7% of S. pneumoniae isolates were drug-resistant. Analysis of resistant genes for H. influenzae and S. pneumoniae isolates, which were stored and sent, demonstrated higher rates of resistance than those observed in susceptibility tests. These results suggest that the increase in insufficient efficacy of usual treatment with combination of ampicillin and cefotaxime is predictableagainst the infections. Therefore, the treatment for the infections should be reconsidered.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 75 (11), 931-939, 2001
The Japanese Association for Infectious Diseases
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Details 詳細情報について
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- CRID
- 1390001205051109632
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- NII Article ID
- 130004330932
- 10009487630
- 10008704097
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 5988532
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- PubMed
- 11768357
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed