TGF‐alphaのマウス卵形嚢感覚上皮に対する効果 7日間器官培養を用いて

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タイトル別名
  • Effect of TGF-alpha on Mice Sensory Epithelia after Culturing Utricles for 7 Days.
  • after Culturing Utricles for 7 Days
  • 7日間器官培養を用いて

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抄録

Using autoradiography with 3H-thymidine, the effect of transforming growth factor (TGF)-alpha was studied after culturing utricles of mice for 7 days. Cell proliferation was induced in the sensory epithelium by TGF-alpha. Compared with utricles cultured for 3 days, many labeled cells were detected in the hair cell layer of the sensory epithelium of utricles cultured for 7 days. These observations suggest that stimulation of the EGF receptors by TGF-alpha binding stimulates cell differentiation as well as cell proliferation in the mature mammalian vestibular sensory epithelium.

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