ENDOSCOPIC EVALUATION OF THE THERAPEUTIC EFFECT OF ENDOSCOPIC VARICEAL LIGATION IN COMBINATION WITH SCLEROTHERAPY FOR ESOPHAGEAL VARICES

• NAKAMURA Shinichi

  Institute of Gastroenterology, Tokyo Women's Medical College

• MITSUNAGA Atsushi

  Institute of Gastroenterology, Tokyo Women's Medical College

• SUZUKI Shigeru

  Institute of Gastroenterology, Tokyo Women's Medical College

• HAYASHI Naoaki

  Institute of Gastroenterology, Tokyo Women's Medical College

Bibliographic Information

Other Title

• 食道静脈瘤に対する結紮術(EVL)と1%Aethoxysklerol静脈瘤外注入併用療法の臨床的検討

Abstract

Endoscopic variceal ligation(EVL)has been popular rapidly, because of usefulrless andeasy technique for the treatment of esophageal varices. But same reports described thatesophageal varices treated by independent EVL tends to recurrent, and EVL is not enough treatment. We performed the combination therapy of EVL and sclerotherapy with 1%Aethoxysk-lerol(1%AS)for esophageal varices(EVL-1%AS therapy). At first, EVL is performed forthe treatment of large varices. And sclerotherapy with 1%AS is added in the follow upstudy. We tried to perform the prophylactic treatment for 35 patients. We achieved theimprovement in 31 (89.5%)out of 35 patients, with the mean number of 7.1±1.9EVLsessions and sclerotherapy with the mean injected volume of 20.0±0.0ml 1%AS in theprimary therapeutic effect. We achieved the remission in 23(74.2%)out of 31 patients, 12months after the treatment, with the mean number of 7.4±2.5EVL sessions and sclerotherapy with the mean mjected volume of 38.4±21.2ml 1%AS. We could improve both theprimary therapeutic effect and the prevention of recurrence by EVL-1%A5 therapycompared with independent EVL. The large varices like F3 levels could be treated successfully by this combination therapy. Recurrent bleeding occurred in 3(8.6%)out of the total patient group by 12 months follow up. We didn't observe the enlargernent ofgastric varices, and recognize the severe side effects. EVL is the useful method for treatment of large and elevated varices. Sclerotherapyby extra-varieeal injection with 1%AS has the effect of mucosal fibrosis, and is theeffective method for treatment of superficial type varices including recurrent lesions. We considered EVL-1%AS therapy had the mutual merits of both methods. In conclusion, EVL-1%AS therapy is the easy and safe technique, and the less invasivemethod for the patients. EVL-1%A5 therapy is the new useful treatment for esophagealvarlces.

Journal

• GASTROENTEROLOGICAL ENDOSCOPY

  GASTROENTEROLOGICAL ENDOSCOPY 38 (3), 813-827, 1996

  Japan Gastroenterological Endoscopy Society

Details

• CRID: 1390282679198377856
• NII Article ID: 130004253960
• NII Article ID: 10008708429
• NII Book ID: AN00192102
• DOI: 10.11280/gee1973b.38.813
• ISSN: 18845738
• ISSN: 03871207
• Web Site: https://search.jamas.or.jp/link/ui/1996175829
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed