EMRLによる分割切除と切除粘膜再構築のための基礎研究および臨床応用  [in Japanese] MULTI-EMRL AND RECONSTRUCTION OF THE RESECTED SPECIMENS : EXPERIMENTAL STUDY FOR THE PURPOSE OF ESTABLISHING RELIABLE TECHNIQUE AND IT'S CLINICAL USE  [in Japanese]

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Abstract

内視鏡的粘膜結紮術を併用した胃粘膜切除術(Endoscopic Mucosal Resection using a Ligating device; EMRL)による分割切除の確実な手技確立と,病変粘膜完全切除の確認に必要な切除粘膜再構築のための手技開発のために,5匹の雑種成犬を用いて基礎実験を施行した.直径20mmの粘膜切除法としては,EVL(Endoscopic Variceal Ligation)の外筒辺縁を手前と左右いずれかの側方(左右いずれかの斜め前方)のマークに重なるように合わせて第1回目の吸引・結紮・切除をして,3回で切除する方法が最も効果的で確実な分割切除法であり,切除面の深度は,分割切除の境界においても粘膜下層(sm3)まで達していた.また,結紮後のクリッピングは,分割切除粘膜の再構築に非常に有効であった.内視鏡的粘膜切除術による分割切除法として,クリッピングを使用したEMRLは簡便かつ確実に施行できる手技と思われた.

We experimented basic examination in 5 mongrel dogs to establish reliable multi-EMRL procedure and useful reconstruction procedure of the resected specimens. It is most effective and reliable technique that, at first EMRL, we applied the cap (EVL device) to both front and one side markes and resect mucosa about ×20 mm in size by 3 times EMRL. The depth of the ulcer base induced by multi-EMRL, even at the borderline between the two resected mucosa, reached submucosal layer (sm3). And it is very effective reconstructed procedure of the specimens by piecemeal resection that clip as mark is punched on the ligated mucosa. These results indicated that multi-EMRL procedure using clip may play a effective and reliable role in the division of mucosal resection.

Journal

  • GASTROENTEROLOGICAL ENDOSCOPY

    GASTROENTEROLOGICAL ENDOSCOPY 38(12), 2840-2847, 1996-12-20

    Japan Gastroenterological Endoscopy Society

References:  9

Cited by:  5

Codes

  • NII Article ID (NAID)
    10008709081
  • NII NACSIS-CAT ID (NCID)
    AN00192102
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03871207
  • Data Source
    CJP  CJPref  J-STAGE 
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