組織学的小裂隙による外リソパ瘻と蝸牛水管との関係 : ヒト側頭骨病理組織学的検討  [in Japanese] Relationship between Perilymphatic Fistula due to Microfissure and the Cochlear Aqueduct : Human Histopathological Study  [in Japanese]

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Author(s)

    • 瀬尾 徹 SEO Toru
    • 兵庫医科大学耳鼻咽喉科学教室 Department of Otolaryngology, Hyogo College of Medicine
    • RYU Jay H
    • ボウマングレイ医科大学耳鼻咽喉科 Department of Otolaryngology, Bowman Gray School of Medicine, Wake Forest University
    • KOHUT Robert I
    • ボウマングレイ医科大学耳鼻咽喉科 Department of Otolaryngology, Bowman Gray School of Medicine, Wake Forest University

Abstract

It was known that patency of fissula ante fenestram (FAF) and microfissure near the round window niche area (RWF) may cause perilymphatic fistula. However, not all patients have symptoms of hearing loss or dysequillibrium. The perilymphatic fluid communicates with the cerebrospinal fluid through the cochlear aqueduct, thus perilymphatic fistula may depend on the aqueduct. This study is to clarify the relationship between histological patency of the cochlear aqueduct and clinical symptom in the case of patent FAF or RWF.<BR>Nineteen human temporal bones with histologically patent FAF or RWF were used in this study. Eight bones were obtained from patients with symptoms of sudden onset hearing loss, progressive hearing loss or vestibular symptoms such as prolonged mild dysequillibrium and positional vertigo, and 11 bones from patients without any hearing or balance problems. Patency of the cochlear aqueduct was scored as one through four. Score one indicated a patent aqueduct and score four indicated a closed aqueduct. The presence of hearing loss or dysequillibrium during life time was determined from clinical charts.<BR>The mean score of symptomatic cases was 2.88 and that of asymptomatic cases was 1.91. The difference between the two groups was significant (p<0.05, Wilcoxon-Mann-Whitney test). This finding suggested that a closed cochlear aqueduct might cause symptoms of perilymphatic fistula in patients with patent FAF or RWF.

Journal

  • Equilibrium Research

    Equilibrium Research 57(1), 64-68, 1998-02-01

    Japan Society for Equilibrium Research

References:  22

Codes

  • NII Article ID (NAID)
    10008710691
  • NII NACSIS-CAT ID (NCID)
    AN00001485
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    03855716
  • Data Source
    CJP  J-STAGE 
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