大分地方における散発下痢症の細菌学的研究, 1985〜1996年  [in Japanese] Bacteriological Studies on Sporabic Diarrhea Diseases in Oita District, 1985-1996  [in Japanese]

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Abstract

散発下痢症は食中毒を含む感染性集団下痢症の背景因子として重要と考えられる. そこで, 約10年間大分地方の散発下痢症の細菌学的検索を行い, その結果を解析した.<BR>1985年から1986年と1989年から1996年の間, 大分市及びその近郊の小児科等の医療機関で細菌性下痢症を疑われた患者の便, 総数1,707検体について細菌学的検索を実施し, 670検体 (約40%) から717株の下痢症起因菌を検出した. 分離菌は, カンピロバクター (40%), サルモネラ (24%), 病原血清型大腸菌 (EPEC) (23%) が大部分を占めた. 腸炎ビブリオ (0.5%) や黄色ブドウ球菌 (2.6%) の検出数は少なかった.<BR>検出率の年次変動を見ると, カンピロバクターが1989年をピークに以後減少し, 反対にサルモネラは増加傾向が続き1992年に順位逆転に至っている. これはサルモネラの中でも近年出現し増加中の血清型Enteritidis (SE) の寄与が大きい. ベロ毒素産生性大腸菌の検出率は低く, 微増傾向にあるものの特異な上昇はみられていない.<BR>以上の結果, 従来の頻発食中毒であるビブリオ症やブドウ球菌症は, 散発下痢症とは殆ど無関係であるが, サルモネラ特に近年食中毒で増加中のSEなど特定の感染性下痢症流行は散発下痢症の背景と密接に関連していることを示唆するものである.

Approaching the problem of how close the sporadic diarrhea diseases correlate with epidemics of infectious diarrheas, including food poisonings, bacteriological studies were made on the characteristics of sporadic diarrheas in the past 10 years and analyzed.<BR>In collaboration with physicians, mostly pediatricians, in Oita district during 1985 to 1986 and 1989 to 1996, a total of 1707 specimens was obtained from diarrhea patients, suspected of bacterial cause. We have isolated 717 strains from 670 specimens (ca 40% of the total). The majority were; <I>Campylobacter, Salmonella</I> and EPEC with the rate of about 40, 24 and 23% respectively. On the other hand, isolation of <I>Vibrio</I> spp. and <I>Staphylococcus</I> were very few.<BR>The yearly trend of detection rates of such major agents were as follows: <I>Campylobacter</I> had the highest rate in the early period, 1989, but thereafter tended to decrease. In contrast, <I>Salmonella</I> continued to increase in rate through the study period until the present when it exceeds that of Campylobacter. This alternation is due primarily to the rapid increase of <I>S.</I> Enteritidis since its recent appearance. VTEC stays at a low rate with a slow increase showing no prevalence so far.<BR>From the above results the following may meet with attention. Vibrios and Staphylococci, known as popular agents for food poisonings, seem unlikely to correlate with sporadic diarrheas. Instead, the evidence that recent food poisoning is often represented by <I>Salmonella</I>, especially <I>S.</I> Enteritidis, suggests that epidemics of infectious diarrhea may be attributed to the background of common sporadic diarrheas.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 71(7), 644-651, 1997-07-20

    The Japanese Association for Infectious Diseases

References:  16

Cited by:  1

Codes

  • NII Article ID (NAID)
    10008721179
  • NII NACSIS-CAT ID (NCID)
    AN00047715
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03875911
  • NDL Article ID
    4268911
  • NDL Source Classification
    ZS9(科学技術--医学--病理学・微生物学・寄生虫学・感染・免疫学・血清学・アレルギー)
  • NDL Call No.
    Z19-193
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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