Clinical Study on Bacteremia in Patients with Liver Cirrhosis
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- MIZUNO Ribun
- Department of Internal Medicine, Meijo Hospital
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- NISHIYAMA Yasunobu
- Department of Clinical Laboratory, Meijo Hospital
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- SHIMIZU Seiichi
- Department of Clinical Laboratory, Meijo Hospital
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- KITAGAWA Motoji
- The Second Department of Internal Medicine, Nagoya University School of Medicine
Bibliographic Information
- Other Title
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- 肝硬変に合併した菌血症の臨床的検討
- カンコウヘン ニ ガッペイシタ キンケッショウ ノ リンショウテキ ケントウ
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Abstract
Infections and fever are frequent in patients with liver cirrhosis. Study on bacteremia in cirrhotic patients has not been reported in Japan. In a 16 year period from 1979 to 1994, we collected 39 cases with 40 episodes and 44 microorganisms of bacteremia for this study. The incidence of bacteremia in cirrhotic hospital admissions was 4.8%(39/808). Gram negative bacteria were the predominant microorganisms of bacteremia (66%, 29/44). Among them, Escherichia coli, Klebsiella pneumoniae, Vibrio sp. were the three most commonly detected microorganisms. Pseudornonas aeruginosa bacteremia has not been detected. Laboratory data of cirrhotic patients showed that positive blood culture patients had significantly lower serum albumin, prothrombin time and hepaplastin test than negative patients. Focal infection could be diagnosed in only 45%(20/44). The mortality rate was 28%(11/39), but the bacteremia related death (by septic shock) were only 2 cases. The other causes of death were hepatic failure in 9 cases. In conclusion, bacteremia is a important complication of liver cirrhosis. Blood culture is necessary in cirrhotic patients with fever.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 70 (5), 456-462, 1996
The Japanese Association for Infectious Diseases
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Details
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- CRID
- 1390001205046934784
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- NII Article ID
- 130004330464
- 10011926191
- 10008723054
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 3968184
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- PubMed
- 8699093
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed