海産藍藻由来魚毒活性物質アンチラトキシンの全合成  [in Japanese] Total Synthesis of Antillatoxin, an Ichthyotoxic Cyclic Lipopeptide from Marine Cyanobacterium Lyngbya majuscula  [in Japanese]

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Author(s)

Abstract

Antillatoxin is an ichthyotoxic cyclic lipopeptide isolated by Gerwick and co-workers from the marine cyanobacterium <I>Lyngbya majuscula</I> collected in Curacao. Although we have finished the stereoselective total synthesis of antillatoxin having the proposed structure with (4<I>S</I>, 5<I>R</I>) -configuration, we have found that the synthetic sample was not identical with the natural one and the proposed structure should be revised. Further our synthetic efforts have culminated in the first total synthesis of antillatoxin in its natural form, proving that the natural one has (4<I>R</I>, 5<I>R</I>) -configuration. In this account, our total synthesis and synthetic studies by other groups will be discussed.

Journal

  • Journal of Synthetic Organic Chemistry, Japan

    Journal of Synthetic Organic Chemistry, Japan 58(7), 634-641, 2000-07-01

    The Society of Synthetic Organic Chemistry, Japan

References:  42

Codes

  • NII Article ID (NAID)
    10008820585
  • NII NACSIS-CAT ID (NCID)
    AN0024521X
  • Text Lang
    JPN
  • Article Type
    REV
  • ISSN
    00379980
  • NDL Article ID
    5397587
  • NDL Source Classification
    ZP11(科学技術--化学・化学工業--有機化学・有機化学工業)
  • NDL Call No.
    Z17-256
  • Data Source
    CJP  NDL  J-STAGE 
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