新皮質ニューロンEPSPの確率的減衰挙動 : Markram-Tsodyks 実験の解析 [in Japanese] Stochastic Depression Behavior of EPSPs in the Neocortical Neurons : Analysis of the Markram-Tsodyks Experiments [in Japanese]
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Stochastic depression behavior of EPSPs which has been investigated experimentally by Markram and Tsodyks is analyzed using a probabilistic postsynapse model involving a 2-state receptor type and the Morris-Lecar equations. The analysis explains the depression and stationary properties of EPSPs on the basis of saturation and recovery characteristics of the receptor mechanisms. Furthermore, the “after pairing effect” is caused by changes in the receptor sensitivity, according to the present model. The model predictions with various action potential frequencies are in good agreement with the experimental results.
- The Brain & Neural Networks
The Brain & Neural Networks 7(4), 115-120, 2000-12-05
Japanese Neural Network Society