色素細胞性母斑:解剖学的部位別の病理組織学的検討 : 第1報 : 顔面病変531例の検討  [in Japanese] The Histopathological Analysis of 531 cases of Melanocytic Nevus of the Face  [in Japanese]

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Abstract

顔面の色素細胞性母斑531例の病理組織学的検討を行った.腫瘍細胞の存在部位により境界型,複合型,真皮型に分類し,さらに臨床病理組織学的にUnna型,Miescher型,Spitz型,Clark型の4型に分類した.なお,単純黒子はClark型の早期病変として分類した.病変の発症時期を考慮して,腫瘍の形態から,非隆起型と隆起型に分類し,非隆起型病変は隆起型病変より早期の病変と判断し検討した.顔面の色素細胞性母斑では,真皮型が531例中382例(71.9%)と最も多く,また臨床病理組織学的にはMiescher型色素細胞性母斑が531例中511例(96.2%)と最も多かった.境界型が531例中15例(2.8%)と非常に少ないことから,境界型の病変では,上皮内悪性黒色腫の可能性も考える必要があると考えた.また,顔面の後天性の色素細胞性母斑の形成機序として,腫瘍細胞が真皮内から発生する可能性と,後天性の病変と認識されている病変の中には,先天性の病変が含まれている可能性があることを指摘した.

We examined 531 HE stained specimens of melanocytic nevi on the face, which were histopathologically diagnosed in our laboratory from April 1990 to March 2000. First, these specimens were divided into two groups, non-elevated and elevated lesions. Two hundred and five cases were non-elevated, and 326 cases were elevated. We think that non-elevated lesions are earlier lesions than elevated ones. Second, based on the location of the tumor cells, these specimens were classified into three groups: junctional, compound, and dermal. Fifteen cases were junctional, 134 cases were compound, and 382 cases were dermal. We clinicopathologically recognized four types of lesions; Unna's, Miescher's, Spitz's, and Clark's nevus, as advocated by Ackerman. There were 3 cases of Unna's nevus, 511 cases of Mieschers's nevus, 1 case of Spitz's nevus, and 16 cases of Clark's nevus in our study. We determined two characteristics that the melanocytic nevus of the face has; one is that the junctional type is rare, and the other is that Miescher's nevus is the most common.

Journal

  • The Japanese Journal of Dermatology

    The Japanese Journal of Dermatology 112(6), 803-810, 2002-05-20

    Japanese Dermatological Association

References:  16

Cited by:  4

Codes

  • NII Article ID (NAID)
    10008880647
  • NII NACSIS-CAT ID (NCID)
    AN00196602
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    0021499X
  • NDL Article ID
    025120485
  • NDL Call No.
    Z19-202
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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