Angiomyofibroblastoma of the Vulva  [in Japanese] Angiomyofibroblastoma of the Vulva  [in Japanese]

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Abstract

44歳女性.右大陰唇皮下の5×3 cm大の腫瘤を主訴に受診.MRIで,大陰唇皮下に境界明瞭な腫瘤を認め,T1強調画像では筋と同程度の信号,T2強調画像では高信号であった.組織学的に,腫瘍は細胞成分が粗で粘液腫様の部分と,卵円型及び紡錘型の細胞が密に増殖している部分より構成されていた.また壁の薄い血管が増生している像を認めた.免疫組織化学的に,腫瘍細胞はvimentin,desmin陽性,CD34,S-100,α-smooth muscle actin,myoglobinは陰性,progesterone receptorは70%の細胞で陽性,estrogen receptorは20%の細胞で陽性であった.臨床像,画像所見および組織学的所見よりangiomyofibroblastoma of the vulvaと診断した.

A 44-year-old woman developed an asymptomatic subcutaneous tumor measuring 3×5 cm in size on her right labium majorum. CT and MRI showed a well-circumscribed lesion. On T1-weighted MR images, the tumor was isointense in relation to muscle, and, on T2-weighted images, it showed hyperintensity. Histopathologically, the tumor was composed of a hypocellular area in loosely edematous stroma and a hypercellular area. Spindle— or oval― shaped tumor cells were arranged with numerous thin-walled vessels. Immunohistochemical examination revealed that the tumor cells were positive for vimentin and desmin and negative for CD34, S-100, α-smooth muscle actin, and myoglobin. A part of the tumor expressed estrogen receptors and progesterone receptors. We diagnosed the tumor as an angiomyofibroblastoma of the vulva.

Journal

  • The Japanese Journal of Dermatology

    The Japanese Journal of Dermatology 112(6), 837-843, 2002-05-20

    Japanese Dermatological Association

References:  27

Cited by:  2

Codes

  • NII Article ID (NAID)
    10008880735
  • NII NACSIS-CAT ID (NCID)
    AN00196602
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    0021499X
  • NDL Article ID
    025120578
  • NDL Call No.
    Z19-202
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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