A Novel Trimerization of 1-Phenylsulfanyl-2,2,2-trifluoroethyl Isocyanide Giving a Dihydropyrimidine Derivative

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Abstract

1-Phenylsulfanyl-2,2,2-trifluoroethyl isocyanide (<b>2a</b>) readily and selectively trimerized to 4,6-bis(phenylsulfanyl)-1-(1-phenylsulfanyl-2,2,2-trifluoroethyl)-5-(2,2,2-trifluoroethylideneamino)-2-trifluoromethyl-1,2-dihydropyrimidine (<b>5</b>) at room temperature, while other <i>α</i>-phenylsulfanyl isocyanides such as phenyl(phenylsulfanyl)methyl isocyanide (<b>2b</b>) are stable. Heating of <b>2b</b> resulted in formation of the corresponding nitrile as well as diphenyl disulfide and [bis(phenylsulfanyl)methyl]benzene.

Journal

  • Bulletin of the Chemical Society of Japan

    Bulletin of the Chemical Society of Japan 69(6), 1763-1767, 1996-06-15

    The Chemical Society of Japan

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Codes

  • NII Article ID (NAID)
    10008904973
  • NII NACSIS-CAT ID (NCID)
    AA00580132
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    00092673
  • NDL Article ID
    4060521
  • NDL Source Classification
    ZP1(科学技術--化学・化学工業)
  • NDL Call No.
    Z53-B35
  • Data Source
    CJP  NDL  J-STAGE 
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